Bacteria Use 91טCrazy Molecular Mechanism91י to Fight Viruses | Science

Some bacteria defend themselves against phages, viruses that look like microscopic spacecraft (pictured), by assembling a gene not in their normal genome. Credit: Victor Padilla-Sanchez CC BY-SA 4.0

MBL Senior Scientist Irina Arkhipova is quoted in this article.

Made-to-order gene could be so toxic that cells only assemble it in emergencies

Viruses plague bacteria as well as people, and some bacteria deploy what one scientist calls a 91לcrazy molecular mechanism91ם to defend themselves, two studies published in Science this month reveal. The bacteria conjure up an entirely new gene that isn91יt normally in their repertoire. This gene, dubbed neo by both groups that unearthed it, then spawns a protein that stymies the viral invaders.

Although the mechanism seems bizarre, 91לthese are excellent papers,91ם says microbiologist Aude Bernheim of the Pasteur Institute, who wasn91יt connected to the research. 91לBoth have very convincing evidence.91ם The findings offer the latest challenge to the misperception that genetic information flows only one way91הfrom DNA to RNA to proteins91הand raise the possibility that similar cryptic genes lurk in other organisms, even humans.

Source: Bacteria Use 91טCrazy Molecular Mechanism91י to Fight Viruses | Science